Placenta (human)
Movie 1: 2D going through: w19 placenta as serial of optical slices
Tissue/pathology:
Human placenta from abortion, w19.
Antibodies:
PEG10 (green)
CD34 (red)
Movie description:
PEG10 (green) is mainly the marker of cytotrophoblast. CD34 (red) depicts the endothelium of blood vessels.
Download high. res. video 请登录哔哩哔哩观看。Movie 2: Same scan as in MOVIE 1 but now in 3D
Tissue/pathology:
Human placenta from abortion, w19.
Antibodies:
PEG10 (green)
CD34 (red)
Movie description:
The vessels and the cytotrophoblast layer are morphologically intact. The CD34 channel has a gradual decrease in signal intensity: this is a technical issue, due to limited laser penetration through this compact structure.
Download high. res. video 请登录哔哩哔哩观看。Movie 3: 2D going through: w40 placenta
Tissue/pathology:
Human placenta, w40, normal delivery time, at the end of pregnancy.
Antibodies:
PEG10 (green)
CD34 (red)
Movie description:
Normal delivery time, as series of optical slices.
Download high. res. video 请登录哔哩哔哩观看。Movie 4: Same as MOVIE 3 but now in 3D
Tissue/pathology:
Human placenta, w40, normal delivery time, at the end of pregnancy.
Antibodies:
PEG10 (green)
CD34 (red)
Movie description:
Both the cytotrophoblast and the blood vessels are already partially atrophied, compared to w19 (MOVIE 2).
Download high. res. video 请登录哔哩哔哩观看。Tissue: Prof. Fredrik Ponten; iDISCO reaction, light sheet microscopy, postprocess and videos: Dr. Csaba Adori